The two dramas have similar themes -- even if you're up against what seems like a mountain of pressure and people against you, you can raise against it and become your best self.
Both has medical trauma genre. Wake up focus more on politic, corruption weak administrative surrounding the hospital, while the doctors worked their heart out, whereas Descendent evolved the romance between military personal and the ER doc
Both male lead were doctor by day and play music or sing in the night club at night. Being a doctor doesn’t mean you have to give up your hobby or entertainment.