Both of them is about a doctor who is obsessed to success and dreams to become hospital director.
Both main character in two dramas (kim myung min and shin ha kyun) is a skillful and arrogant doctor but have good heart inside them.
Brain is mainly around neurosurgery department while white tower in heart surgery department.
However, the situation, and the way of struggling is different for both dramas.
There is a nice love story in brain but no love story focused in white tower.

Both of them are science fiction thriller which deals epidemic virus that affects population inkorea.
If you like this kind of movies, you should watch both.

Have many similarities.
Both of them about siblings who suffered in childhood because of one devil villain who destroyed their family. Then, they grow up and have revenge towards the villain.
Both of them also have background of 1980s-1990s

Aside from family revenge things, they have other different themes.
East of eden involve switching brothers at birth and their consequences in their future life