Hyde, Jekyll and Me
I'm not sure if this counts as a disability but one of the main leads in White Christmas has a neurological thing that affects his emotions. 

Those are the only two I can think of that haven't already been said. 

I second "Falling For Innocence" ~ There's also "Cain and Abel" where one male lead has an illness (won't spoil it) and the other was born three? months premature; and one of the lead females has heart problems.
please just watch my most favorite kdrama http://mydramalist.com/1146-im-sorry-i-love-you if you like to watch tragic kind of saddnes
How about these:
It's OK, that's Love; Kill Me, Heal Me; Always (movie with So Ji Sub); A Moment to Remember; Angel Eyes; Heaven's Postman; Stairway to Heaven; A Beautiful Life (I love this movie); Falling in Love with Soon Jung.
Kill Me Heal Me
Hyde, Jekyll, Me
You Who Came from the Star
The Princess Man (in the end the male lead became blind)
Birth of a Beauty
Gu Family Book (I guess?)
Blade Man (I guess?)
Nirvana in Fire
Sound of the Desert
Snow Lotus (in the end the lead actor is in coma)

the male lead has memory loss
Secret Garden
Save the Last Dance for Me
The Master's  Sun
Iljimae


Hi. I want watch korean or japanese drama about blindness. Please inform to me what drama about blindness. Tq. ????

Sick Male Lead

Boku no ita Jikan

Nirvana in Fire

Love in Between

Falling for innocence

Kill me heal me

It's ok that's love

Memory love

Listening snow tower

I guess no one mentioned these two gems




'Time' https://mydramalist.com/28710-time  ... Am sure it will be perfect... He has a brain tumor.. 


'The Crowned Clown' Not only the Male lead is sick but also the drama is epic!