A Beautiful Mind, ML is empathy stunted
A Robot in the Orange Orchard, ML suffers from haphephobia
About Is Love, ML suffers from haphephobia
Amidst a Snowstorm of Love, ML represses himself due to his history of emotional outbursts and actions
Clean with Passion for Now, ML suffers from mysophobia
Crazy Love, ML let trauma define his life
Dating in the Kitchen, ML has allowed his parent to dictate his life
Hyde, Jekyll, Me, ML suffers from dissociative identity disorder
It's Okay, That's Love, ML suffers from schizophrenia
Kill Me, Heal Me, ML suffers from multiple personalities, memory loss, and dissociation
Love Crossed, ML is a literal prisoner of an entertainment conglomeration from a young age
Love Me If You Dare, ML is extremely intelligent, but has a low EQ
My Love from the Star, ML is a repressed, isolated alien
My Mister (not so much reclusive as he is repressed, and some will say she wasn't a love interest)
Promise in the Summer, ML suffers from haphephobia
Protect the Boss, ML suffers from panic disorder, OCD
Radio Romance, ML suffers from trauma: insomnia, depression
Rich Man, ML suffers from prosopagnosia
Smile Code, ML suffers alexithymia from trauma
Snowfall, ML is a vampire (censored one with no fangs or neck biting) who has isolated himself from everyone, human and vampire alike
Sweet Sweet, ML suffers from aphasia
The Atypical Family, ML suffers from depression
The Beauty Inside, ML suffers from prosopagnosia
The Master's Sun, ML suffers from trauma
Story of Kunning Palace, ML suffers from trauma
Till the End of the Moon, ML is evil and hated
Why Is He Still Single?, ML is neurodivergent, low EQ, and suffers from OCD
Your Sensibility My Destiny, ML feels no emotions or senses
In a switch from the "she fixes him" or "he fixes her" scenario, there is Romantics Anonymous, where the leads suffer from phobia, social anxiety disorder, OCD, and various other conditions, and they embrace them and each other. It was refreshing to have a drama that acknowledged some disorders won't be fixed overnight even when you're loved and happy.
Some above are wonderful, many are average, and some I wouldn't watch again, but they all fit your parameters.