No, I don't have this problem. If I get invested in an OTP, it's because the ACTORS have done a good job and/or had good onscreen chemistry. So I'll look out for those actors again, to see if their skill at acting extends beyond one specific Drama. I've never shipped an OTP IRL, but have been pleasantly surprised when it happens anyway, as with Nigeru Wa Haji and Le Coup de Foudre. Knowing those actors are IRL partners would not stop me watching them act with others, as I know they're good at their job, which is pretending.